Thalidomide-O-amido-C6-NH2 hydrochloride

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TargetMol
Product Code: TAR-T18816
Supplier: TargetMol
CodeSizePrice
TAR-T18816-1mg1mg£193.00
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TAR-T18816-5mg5mg£372.00
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TAR-T18816-10mg10mg£518.00
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TAR-T18816-25mg25mg£791.00
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Quantity:
TAR-T18816-50mg50mg£1,058.00
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TAR-T18816-100mg100mg£1,396.00
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Quantity:
TAR-T18816-500mg500mg£2,713.00
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
Thalidomide-O-amido-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker. It can be used in the synthesis of PROTACs.
CAS:
2376990-31-5
Formula:
C21H27ClN4O6
Molecular Weight:
466.92
Pathway:
Others|PROTAC
Purity:
0.9733
SMILES:
Cl.NCCCCCCNC(=O)COc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
Target:
E3 Ligase Ligand-Linker Conjugate|Others

References

1. Bradner J, et al. Targeted protein degradation to attenuate adoptive t-cell therapy associated adverse inflammatory responses. WO 2017024318 A1