SRX3207
Code | Size | Price |
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TAR-T22430-1mg | 1mg | £185.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T22430-5mg | 5mg | £362.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T22430-10mg | 10mg | £507.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T22430-25mg | 25mg | £775.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T22430-50mg | 50mg | £1,018.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T22430-100mg | 100mg | £1,372.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T22430-500mg | 500mg | £2,681.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
SRX3207 is a novel dual PI3K-Syk inhibitor with IC50 of 244 nM, 388 nM, 9790 nM, 39.9 nM, 31200 nM, 3070 nM, 3070 nM for PI3K alpha, PI3K delta, PI3K gamma, Syk, Zap70, BRD41, BRD42, respectively. SRX3207 can relieve tumor immunosuppression.
CAS:
2254693-15-5
Formula:
C29H29N7O3S
Molecular Weight:
555.65
Pathway:
Angiogenesis|Others|PI3K/Akt/mTOR signaling|Tyrosine Kinase/Adaptors
Purity:
0.98
SMILES:
0
Target:
Syk|Others|PI3K
References
Shweta Joshi, et al. Macrophage Syk?PI3K? Inhibits Antitumor Immunity: SRX3207, a Novel Dual Syk?PI3K Inhibitory Chemotype Relieves Tumor Immunosuppression. Molecular Cancer Therapeutics. 2020.
Shweta Joshi, et al. Macrophage Syk-PI3K? Inhibits Antitumor Immunity: SRX3207, a Novel Dual Syk-PI3K Inhibitory Chemotype Relieves Tumor Immunosuppression. Mol Cancer Ther. 2020 Mar;19(3):755-764.