GSK106
| Code | Size | Price |
|---|
| TAR-T24104-25mg | 25mg | £570.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
GSK106 is a negative control used in binding and functional assays for PAD4 inhibitors.
CAS:
1652591-82-6
Formula:
C24H28ClN5O
Molecular Weight:
437.97
Purity:
0.98
SMILES:
Cl.CCn1c(cc2ccccc12)-c1nc2ccc(cc2n1C)C(=O)N1CCCC(N)C1
References
1. Jones, J.E., Causey, C.P., Knuckley, B., et al. Protein arginine deiminase 4 (PAD4): Current understanding and future therapeutic potential. Curr. Opin. Drug Discov. Devel. 12(5), 616-627 (2009).
2. Lewis, H.D., Liddle, J., Coote, J.E., et al. Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation. Nat. Chem. Biol. 11(3), 189-191 (2015).