IM-54

TargetMol
Product Code: TAR-T24160
Supplier: TargetMol
CodeSizePrice
TAR-T24160-1mg1mg£112.00
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TAR-T24160-5mg5mg£173.00
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Quantity:
TAR-T24160-10mg10mg£225.00
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Quantity:
TAR-T24160-25mg25mg£332.00
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Quantity:
TAR-T24160-50mg50mg£461.00
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Quantity:
TAR-T24160-100mg100mg£630.00
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Quantity:
TAR-T24160-500mg500mg£1,219.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
IM-54 is a cell-permeable, effective, and selective necrosis inhibitor.
CAS:
861891-50-1
Formula:
C19H23N3O2
Molecular Weight:
325.4
Pathway:
MAPK
Purity:
0.9905
SMILES:
O=C1C(NCCCCC)=C(C(=O)N1C)C2=CN(C=3C=CC=CC23)C
Target:
MLK

References

1. Dodo K, et al. Indolylmaleimide Derivative IM-17 Shows Cardioprotective Effects in Ischemia-Reperfusion Injury. ACS Med Chem Lett. 2018 Jan 29;9(3):182-187. 2. Dodo K, et al. Structure-Activity Relationship Study of 3-Amino-2-indolyllactam Derivatives: Development of Inhibitors of Oxidative Stress-Induced Necrosis. Chem Pharm Bull (Tokyo). 2016;64(7):886-98. 3. Zeng F, Sherry JP, Bols NC. Evaluating the toxic potential of benzothiazoles with the rainbow trout cell lines, RTgill-W1 and RTL-W1. Chemosphere. 2016 Jul;155:308-318. 4. Zeng F, Sherry JP, Bols NC. Use of the rainbow trout cell lines, RTgill-W1 and RTL-W1 to evaluate the toxic potential of benzotriazoles. Ecotoxicol Environ Saf. 2016 Feb;124:315-323.