Otaplimastat
| Code | Size | Price |
|---|
| TAR-T24817-25mg | 25mg | £1,048.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T24817-50mg | 50mg | £1,564.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
SP-8203 is a reactive oxygen species inhibitor and superoxide dismutase stimulant.
CAS:
1176758-04-5
Formula:
C28H34N6O5
Molecular Weight:
534.61
Purity:
0.98
SMILES:
CC(N(CCCN1C(NC2=C(C=CC=C2)C1=O)=O)CCCCNCCCN3C(NC4=C(C=CC=C4)C3=O)=O)=O
References
1. Han SY, Yoon I, Chin YW, Cho IW, Lee MG, Choi YH. Pharmacokinetic interaction between metoprolol and SP-8203 in rats: competitive inhibition for the metabolism of metoprolol by SP-8203 via hepatic CYP2D subfamily. Xenobiotica. 2012 Oct;42(10):1017-27. doi: 10.3109/00498254.2012.663117. Epub 2012 May 9. PubMed PMID: 22568632.
2. Noh SJ, Lee JM, Lee KS, Hong HS, Lee CK, Cho IH, Kim HS, Suh YH. SP-8203 shows neuroprotective effects and improves cognitive impairment in ischemic brain injury through NMDA receptor. Pharmacol Biochem Behav. 2011 Nov;100(1):73-80. doi: 10.1016/j.pbb.2011.07.018. Epub 2011 Aug 1. PubMed PMID: 21835192.
3. Noh SJ, Lee SH, Shin KY, Lee CK, Cho IH, Kim HS, Suh YH. SP-8203 reduces oxidative stress via SOD activity and behavioral deficit in cerebral ischemia. Pharmacol Biochem Behav. 2011 Mar;98(1):150-4. doi: 10.1016/j.pbb.2010.12.014. Epub 2010 Dec 21. PubMed PMID: 21172384.
4. Lee JH, Choi YH, Suh JH, Kang HE, Lee TH, Cho IH, Lee MG. Dose-dependent pharmacokinetics of SP-8203 in rats. Biopharm Drug Dispos. 2010 Jul;31(5-6):358-61. doi: 10.1002/bdd.713. PubMed PMID: 20578211.