Enflicoxib
| Code | Size | Price |
|---|
| TAR-T27233-50mg | 50mg | £870.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T27233-100mg | 100mg | £1,364.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
E-6087 is a cyclooxygenase 2 (COX-2) inhibitor potentially for the treatment of osteoarthritis and pain.
CAS:
251442-94-1
Formula:
C16H12F5N3O2S
Molecular Weight:
405.34
Purity:
0.98
SMILES:
NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1ccc(F)cc1F)C(F)(F)F
References
1. Salgado L, Encina G, Farran R, Puig S, Mart?nez L. Enantioselective HPLC determination of E-6087, a new COX-2 inhibitor, in human plasma: Validation and pharmacokinetic application. Chirality. 2004 May 15;16(5):302-8. PubMed PMID: 15069660.
2. Reinoso RF, Farr?n R, Moragon T, Garc?a-Soret A, Mart?nez L. Development and validation of two chromatographic methods for the quantification of E-6087 and one of its metabolites, E-6132, in rat plasma. J Pharm Biomed Anal. 2001 Mar;24(5-6):897-911. PubMed PMID: 11248483.
3. Reinoso RF, Farr?n R, Morag?n T, Garc?a-Soret A, Mart?nez L. Pharmacokinetics of E-6087, a new anti-inflammatory agent, in rats and dogs. Biopharm Drug Dispos. 2001 Sep;22(6):231-42. PubMed PMID: 11754039.
4. Wagemakers M, van der Wal GE, Cuberes R, Alvarez I, Andr?s EM, Buxens J, Vela JM, Moorlag H, Mooij JJ, Molema G. COX-2 Inhibition Combined with Radiation Reduces Orthotopic Glioma Outgrowth by Targeting the Tumor Vasculature. Transl Oncol. 2009 Mar;2(1):1-7. PubMed PMID: 19252746; PubMed Central PMCID: PMC2647697.