TargetMol

Icariin

Product Code:
 
TAR-T2855
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2855-50mg50mg£97.00
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TAR-T2855-100mg100mg£109.00
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TAR-T2855-1mL1 mL * 10 mM (in DMSO)£114.00
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This product comes from: United States.
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Further Information

Bioactivity:
Icariin is a flavonol glycoside, inhibiting PDE5 and PDE4 activities. Icariin also is a PPARα activator.
CAS:
489-32-7
Formula:
C33H40O15
Molecular Weight:
676.668
Pathway:
Metabolism; Autophagy; DNA Damage/DNA Repair
Purity:
0.9804
SMILES:
COc1ccc(cc1)-c1oc2c(CC=C(C)C)c(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)cc(O)c2c(=O)c1O[C@@H]1O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O
Target:
PDE; PPAR; Autophagy

References

1. Song YX, et al. Chin J Integr Med. 2015 Nov 20. 2. Liang Y, Xu Z, Wu X, et al. Inhibition of hyperpolarization-activated cyclic nucleotide-gated channels with natural flavonoid quercetin[J]. Biochemical and Biophysical Research Communications. 2020 3. Gao Y, Xu G, Ma L, et al. Icarisid I specifically facilitates ATP or nigericin-induced NLRP3 inflammasome activation and causes idiosyncratic hepatotoxicity[J]. Cell Communication and Signaling. 2020 4. Gao Y, Xu G, Ma L, et al. Icariside I specifically facilitates ATP or nigericin-induced NLRP3 inflammasome activation and causes idiosyncratic hepatotoxicity[J]. Cell Communication and Signaling. 2021, 19(1): 1-14.