S-5751
Code | Size | Price |
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TAR-T28651-5mg | 5mg | £930.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28651-50mg | 50mg | £1,821.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28651-100mg | 100mg | £2,319.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
S-5751, a prostanoid DP (DP1) antagonist, is used potentially for the treatment of bronchial asthma.
CAS:
209268-36-0
Formula:
C25H31NO4S
Molecular Weight:
441.59
Purity:
0.98
SMILES:
[H][C@@]12C[C@@]([H])([C@H](NC(=O)c3csc4ccc(O)cc34)[C@@H](CC=C/CCCC(O)=O)C1)C2(C)C
References
1. Arimura A, Yasui K, Kishino J, Asanuma F, Hasegawa H, Kakudo S, Ohtani M, Arita H. Prevention of allergic inflammation by a novel prostaglandin receptor antagonist, S-5751. J Pharmacol Exp Ther. 2001 Aug;298(2):411-9. PubMed PMID: 11454901.
2. Shichijo M, Arimura A, Hirano Y, Yasui K, Suzuki N, Deguchi M, Abraham WM. A prostaglandin D2 receptor antagonist modifies experimental asthma in sheep. Clin Exp Allergy. 2009 Sep;39(9):1404-14. doi: 10.1111/j.1365-2222.2009.03275.x. PubMed PMID: 19486034.
3. Hirano Y, Shichijo M, Ikeda M, Kitaura M, Tsuchida J, Asanuma F, Yanagimoto T, Furue Y, Imura K, Yasui K, Arimura A. Prostanoid DP receptor antagonists suppress symptomatic asthma-like manifestation by distinct actions from a glucocorticoid in rats. Eur J Pharmacol. 2011 Sep;666(1-3):233-41. doi: 10.1016/j.ejphar.2011.05.003. PubMed PMID: 21596028.
4. Yasui K, Asanuma F, Hirano Y, Shichijo M, Deguchi M, Arimura A. Contribution of prostaglandin D2 via prostanoid DP receptor to nasal hyperresponsiveness in guinea pigs repeatedly exposed to antigen. Eur J Pharmacol. 2008 Jan 14;578(2-3):286-91. PubMed PMID: 17927976.