TargetMol

Honokiol

Product Code:
 
TAR-T3001
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3001-1mL1 mL * 10 mM (in DMSO)£111.00
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TAR-T3001-50mg50mg£111.00
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TAR-T3001-100mg100mg£121.00
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This product comes from: United States.
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Further Information

Bioactivity:
Honokiol is the active principle of magnolia extract. It inhibits the activation of Akt and enhances the phosphorylation of ERK1/ERK2.
CAS:
35354-74-6
Formula:
C18H18O2
Molecular Weight:
266.34
Pathway:
Microbiology/Virology; MAPK; Proteases/Proteasome; Autophagy; PI3K/Akt/mTOR signaling; Cytoskeletal Signaling
Purity:
0.9987
SMILES:
Oc1ccc(cc1CC=C)-c1cc(CC=C)ccc1O
Target:
ERK; HCV Protease; MEK; Akt; Autophagy

References

1. Bai X, et al. J Biol Chem, 2003, 278(37), 35501-35507. 2. Ishitsuka K, et al. Blood, 2005, 106(5), 1794-800. 3. Battle TE, et al. Blood, 2005, 106(2), 690-697. 4. Wang T, et al. World J Gastroenterol, 2004, 10(15), 2205-2208. 5. Ahn KS, et al. Mol Cancer Res, 2006, 4(9), 621-633. 6. Godugu C, et al. Honokiol nanomicellar formulation produced increased oral bioavailability and anticancer effects in triple negative breast cancer (TNBC). Colloids Surf B Biointerfaces. 2017 Jan 23;153:208-219 7. Lee TY, et al. Honokiol as a specific collagen receptor glycoprotein VI antagonist on human platelets: Functional ex vivo and in vivo studies. Sci Rep. 2017 Jan 5;7:40002