MitoPQ
| Code | Size | Price |
|---|
| TAR-T33412-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T33412-50mg | 50mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
MITOPQ (MITOPARAQUAT) is a redox cycler. MITOPQ selectively accumulates in membrane potential-driven mitochondrial matrix. In the matrix, MITOPQ selectively increases the production of superoxides in mitochondria through the REDOX cycle at the flavin site of complex I. MITOPQ selectively generates superoxides within mitochondria and is a useful tool for studying the many roles of mitochondrial superoxides in pathology and REDOX signaling in cells and in vivo.
CAS:
1821370-28-8
Formula:
C39H46I3N2P
Molecular Weight:
954.498
Purity:
0.98
SMILES:
[I-].[I-].[I-].C[n+]1ccc(cc1)-c1cc[n+](CCCCCCCCCC[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1
References
Robb EL, Gawel JM, Aksentijevi? D, Cochem? HM, Stewart TS, Shchepinova MM, Qiang H, Prime TA, Bright TP, James AM, Shattock MJ, Senn HM, Hartley RC, Murphy MP. Selective superoxide generation within mitochondria by the targeted redox cycler MitoParaquat. Free Radic Biol Med. 2015 Dec;89:883-94. doi: 10.1016/j.freeradbiomed.2015.08.021. PubMed PMID: 26454075.