Redaporfin
| Code | Size | Price |
|---|
| TAR-T34278-25mg | 25mg | £970.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Redaporfin, also known as F-2BMet or LUZ-11, is a photosensitizer for Photodynamic Therapy (PDT) of cancer. Redaporfin showed a high efficacy in the treatment of male BALB/c mice with subcutaneously implanted colon (CT26) tumours. Vascular-PDT with 1.5 mg/kg redaporfin and a light dose of 74 J/cm? led to the complete tumour regression in 83% of the mice.
CAS:
1224104-08-8
Formula:
C48H38F8N8O8S4
Molecular Weight:
1135.11
Purity:
0.98
SMILES:
CNS(=O)(=O)c1ccc(F)c(c1F)-c1c2CCc(n2)c(-c2c(F)ccc(c2F)S(=O)(=O)NC)c2ccc([nH]2)c(c2CCc(n2)c(-c2c(F)ccc(c2F)S(=O)(=O)NC)c2ccc1[nH]2)-c1c(F)ccc(c1F)S(=O)(=O)NC
References
Rocha LB, Schaberle F, D?browski JM, Sim?es S, Arnaut LG. Intravenous Single-Dose Toxicity of Redaporfin-Based Photodynamic Therapy in Rodents. Int J Mol Sci. 2015 Dec 8;16(12):29236-49. doi: 10.3390/ijms161226162. PubMed PMID: 26670231.