TargetMol

Sinapinic Acid

Product Code:
 
TAR-T3753
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T3753-1mL1 mL * 10 mM (in DMSO)£111.00
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TAR-T3753-100mg100mg£117.00
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Further Information

Bioactivity:
Sinapic acid protects the rat liver from CCl4-induced inflammation, most likely by acting as a free radical scavenger and modulator of NF-κB p65 activation and proinflammatory cytokine expression. Sinapic acid with antioxidant role protects cardiac cells and its functions from I/R induced oxidative stress. Sinapic acid is a potentially useful agent for the protection against liver fibrosis and cirrhosis. Sinapic acid prevents the alterations in the levels of lipids and lipoproteins by virtue of its anti-lipidaemic effect in isoproterenol induced myocardial infarcted rats. Sinapic acid ameliorates hyperglycemia through PLC-PKC signals to enhance the glucose utilization in diabetic rats.
CAS:
530-59-6
Formula:
C11H12O5
Molecular Weight:
224.212
Pathway:
DNA Damage/DNA Repair; NF-κb; Chromatin/Epigenetic; Immunology/Inflammation; Apoptosis; Endocrinology/Hormones; Metabolism
Purity:
0.9992
SMILES:
COc1cc(C=CC(O)=O)cc(OC)c1O
Target:
Apoptosis; RAAS; Reactive Oxygen Species; HDAC

References

Cherng YG,et al.Antihyperglycemic action of sinapic acid in diabetic rats. 2013 Dec 11;61(49):12053-9. Shin DS,et al.Effect of sinapic acid against carbon tetrachloride-induced acute hepatic injury in rats. 2013 May;36(5):626-33.