Trioxsalen
| Code | Size | Price |
|---|
| TAR-T4558-25mg | 25mg | £94.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T4558-1mL | 1 mL * 10 mM (in DMSO) | £109.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Trioxsalen is a furanocoumarin and a psoralen derivative, in conjunction with UV-A for phototherapy treatment of vitiligo and hand eczema. After photoactivation it creates interstrand cross-links in DNA, which can cause programmed cell death.
CAS:
3902-71-4
Formula:
C14H12O3
Molecular Weight:
228.247
Pathway:
Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
Purity:
1
SMILES:
Cc1cc2cc3c(C)cc(=O)oc3c(C)c2o1
Target:
DNA Alkylator/Crosslinker; DHFR
References
Hadjipavlou-Litina D,etal.Trioxsalen derivatives with lipoxygenase inhibitory activity.J Enzyme Inhib Med Chem. 2009 Dec;24(6):1351-6.