O6-Benzylguanine
Code | Size | Price |
---|
TAR-T7539-1mL | 1 mL * 10 mM (in DMSO) | £95.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T7539-25mg | 25mg | £104.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T7539-50mg | 50mg | £120.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T7539-100mg | 100mg | £148.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
O6-Benzylguanine is a guanine analog with antineoplastic activity,and is a potent O6-alkylguanine DNA alkyltransferase (AGT) inactivator.
CAS:
19916-73-5
Formula:
C12H11N5O
Molecular Weight:
241.254
Pathway:
Apoptosis; DNA Damage/DNA Repair; Cell Cycle/Checkpoint
Purity:
0.98
SMILES:
Nc1nc(OCc2ccccc2)c2nc[nH]c2n1
Target:
Apoptosis; DNA Alkylation; DNA/RNA Synthesis
References
Tacastacas J D , Chan D V , Carlson S . Evaluation of O6-Benzylguanine?Potentiated Topical Carmustine for Mycosis FungoidesA Phase 1-2 Clinical Trial[J]. JAMA Dermatology, 2017, 153(5):p?gs. 413-420.
Dolan M E , Pegg A E . O6-Benzylguanine and its role in chemotherapy[J]. Clinical Cancer Research, 1997, 3(6):837-847.