TargetMol

Artesunate

Product Code:
 
TAR-T0433
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T0433-50mg50mg£111.00
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Quantity:
TAR-T0433-1mL1 mL * 10 mM (in DMSO)£115.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T0433-100mg100mg£134.00
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
Artesunate is part of the artemisinin group of drugs that treat malaria. It is a semi-synthetic derivative of artemisinin that is water-soluble and may therefore be given by injection. It is on the World Health Organization's List of Essential Medicines.
CAS:
88495-63-0
Formula:
C19H28O8
Molecular Weight:
384.425
Pathway:
Microbiology/Virology; JAK/STAT signaling; Cell Cycle/Checkpoint; Apoptosis; Stem Cells
Purity:
0.9991
SMILES:
C[C@@H]1CC[C@H]2[C@@H](C)[C@H](OC(=O)CCC(O)=O)O[C@@H]3O[C@@]4(C)CC[C@@H]1[C@@]23OO4
Target:
Virus Protease; Ferroptosis; STAT; Parasite

References

1. Xu N, et al. Int J Med Sci. 2015, 12(6):524-529. 2. Lian S, et al. Oncol Rep. 2016, 36(2):984-1990. 3. Qiao SK, et al. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2016, 24(1):131-137. 4. Lisewski AM, et al. Cell. 2014, 158(4):916-928. 5. Luo J, et al.Radiat Oncol. 2014, 9:84. 6. Wang B, et al. Artesunate sensitizes ovarian cancer cells to cisplatin by downregulating RAD51. Cancer Biol Ther. 2015;16(10):1548-56. 7. Ilamathi M, et al. Artesunate as an Anti-Cancer Agent Targets Stat-3 and Favorably Suppresses Hepatocellular Carcinoma. Curr Top Med Chem. 2016;16(22):2453-63. 8. Bowden G D, Land K M, O'Connor R M, et al. High-throughput screen of drug repurposing library identifies inhibitors of Sarcocystis neurona growth[J]. International Journal for Parasitology: Drugs and Drug Resistance. 2018 Apr?8(1): 137-144.