TargetMol

Chenodeoxycholic acid

Product Code:
 
TAR-T0847
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T0847-1mL1 mL * 10 mM (in DMSO)£111.00
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Quantity:
TAR-T0847-100mg100mg£115.00
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Further Information

Bioactivity:
Chenodiol is a bile acid, usually conjugated with either glycine or taurine. It acts as a detergent to solubilize fats for intestinal absorption and is reabsorbed by the small intestine. It is used as cholagogue, a choleretic laxative, and to prevent or dissolve gallstones.
CAS:
474-25-9
Formula:
C24H40O4
Molecular Weight:
392.58
Pathway:
Metabolism; Membrane transporter/Ion channel; Autophagy
Purity:
0.9997
SMILES:
C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
Target:
Potassium Channel; FXR; Endogenous Metabolite; Autophagy

References

1. Stauffer AT, et al. J Biol Chem,2002, 277(29), 26286-26292. 2. Casaburi I, et al. Cell Cycle, 2012, 11(14), 2699-2710. 3. Kawabe Y, et al. Biochem Biophys Res Commun,1995, 208(1), 405-411. 4. Ao M, et al. Am J Physiol Cell Physiol,2013, 305(4), C447-456. 5. Noh K, et al. Drug Metab Dispos,2011, 39(8), 1451-1459. 6. Sun L, Xie C, Wang G, et al. Gut microbiota and intestinal FXR mediate the clinical benefits of metformin[J]. Nature medicine. 2018 Dec;24(12):1919-1929.