Flufenamic acid
Code | Size | Price |
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TAR-T0858-50mg | 50mg | £99.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T0858-1mL | 1 mL * 10 mM (in DMSO) | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T0858-100mg | 100mg | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T0858-200mg | 200mg | £119.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Flufenamic acid is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint disorders and administered by mouth and topically.
CAS:
530-78-9
Formula:
C14H10F3NO2
Molecular Weight:
281.234
Pathway:
Microbiology/Virology; Neuroscience; Immunology/Inflammation; Chromatin/Epigenetic; Metabolism; PI3K/Akt/mTOR signaling; Membrane transporter/Ion channel
Purity:
0.9971
SMILES:
OC(=O)c1ccccc1Nc1cccc(c1)C(F)(F)F
Target:
Potassium Channel; Calcium Channel; Chloride channel; COX; AMPK; Parasite
References
1. White MM, et al. Mol Pharmacol, 1990, 37(5), 720-724.
2. G?gelein H, et al. FEBS Lett, 1990, 268(1), 79-82.
3. Baures PW, et al. Bioorg Med Chem, 1999, 7(7), 1339-1347.
4. Hill K, et al. Neuropharmacology, 2004, 47(3), 450-460.
5. Ghamari-Langroudi M et al. J Physiol, 2002, 545(Pt 2), 537-542.
6. Pongkorpsakol P, et al. Flufenamic acid protects against intestinal fluid secretion and barrier leakage in a mouse model of Vibrio cholerae infection through NF-?B inhibition and AMPK activation. Eur J Pharmacol. 2017 Mar 5;798:94-104.
7. Pongkorpsakol P, et al. Cellular mechanisms underlying the inhibitory effect of flufenamic acid on chloride secretion in human intestinal epithelial cells. J Pharmacol Sci. 2017 Jun;134(2):93-100.