2-Iodomelatonin

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TargetMol
Product Code: TAR-T10073
Supplier: TargetMol
CodeSizePrice
TAR-T10073-5mg5mg£102.00
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TAR-T10073-1mL1 mL * 10 mM (in DMSO)£105.00
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TAR-T10073-10mg10mg£122.00
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TAR-T10073-25mg25mg£173.00
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TAR-T10073-50mg50mg£242.00
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TAR-T10073-100mg100mg£349.00
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TAR-T10073-200mg200mg£485.00
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TAR-T10073-500mg500mg£733.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
2-Iodomelatonin is a potent agonist of melatonin receptor 1 (MT1, Ki: 28 pM), it is more 5-fold selective for MT1 over MT2.
CAS:
93515-00-5
Formula:
C13H15IN2O2
Molecular Weight:
358.179
Pathway:
GPCR/G Protein
Purity:
0.98
SMILES:
COc1ccc2[nH]c(I)c(CCNC(C)=O)c2c1
Target:
Melatonin Receptor

References

Tomkinson A, et al. A murine IL-4 receptor antagonist that inhibits IL-4- and IL-13-induced responses prevents antigen-induced airway eosinophilia and airway hyperresponsiveness. J Immunol. 2001 May 1;166(9):5792-800. Wang X, et al. The melatonin MT1 receptor axis modulates mutant Huntingtin-mediated toxicity.J Neurosci. 2011 Oct 12;31(41):14496-507.