Adoprazine

TargetMol
Product Code: TAR-T10249
Supplier: TargetMol
CodeSizePrice
TAR-T10249-1mg1mg£135.00
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TAR-T10249-2mg2mg£165.00
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TAR-T10249-5mg5mg£229.00
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TAR-T10249-1mL1 mL * 10 mM (in DMSO)£245.00
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TAR-T10249-10mg10mg£341.00
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TAR-T10249-25mg25mg£544.00
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TAR-T10249-50mg50mg£744.00
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TAR-T10249-100mg100mg£1,002.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Adoprazine is a potential atypical antipsychotic bearing potent D2 receptor antagonist and 5-HT1A receptor agonist properties.
CAS:
222551-17-9
Formula:
C24H24FN3O2
Molecular Weight:
405.46
Purity:
0.9944
SMILES:
FC1=CC=C(C=C1)C=2C=NC=C(C2)CN3CCN(C=4C=CC=C5OCCOC54)CC3

References

1. Auclair AL, Kleven MS, Barret-Gr?voz C, Barreto M, Newman-Tancredi A, Depoort?re R. Differences among conventional, atypical and novel putative D(2)/5-HT(1A) antipsychotics on catalepsy-associated behaviour in cynomolgus monkeys. Behav Brain Res. 2009 N 2. Lange JH, Reinders JH, Tolboom JT, Glennon JC, Coolen HK, Kruse CG.Principal component analysis differentiates the receptor binding profiles of three antipsychotic drug candidates from current antipsychotic drugs. J Med Chem. 2007 Oct 18;50(21):5103-8. 3. McCreary AC, Glennon JC, Ashby CR Jr, Meltzer HY, Li Z, Reinders JH, Hesselink MB, Long SK, Herremans AH, van Stuivenberg H, Feenstra RW, Kruse CG. SLV313 (1-(2,3-dihydro-benzo[1,4]dioxin-5-yl)-4- [5-(4-fluoro-phenyl)-pyridin-3-ylmethyl]-piperazine monoh 4. Feenstra RW, van den Hoogenband A, Stroomer CN, van Stuivenberg HH, Tulp MT, Long SK, van der Heyden JA, Kruse CG. SAR study of 1-aryl-4-(phenylarylmethyl)piperazines as ligands for both dopamine D2 and serotonin 5-HT1A receptors showing varying degrees 5. Cosi C, Carilla-Durand E, Assi? MB, Ormiere AM, Maraval M, Leduc N, Newman-Tancredi A. Partial agonist properties of the antipsychotics SSR181507, aripiprazole and bifeprunox at dopamine D2 receptors: G protein activation and prolactin release. Eur J Ph