TargetMol

Camptothecin

Product Code:
 
TAR-T1123
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T1123-100mg100mg£107.00
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Quantity:
TAR-T1123-1mL1 mL * 10 mM (in DMSO)£111.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T1123-500mg500mg£180.00
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This product comes from: United States.
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Further Information

Bioactivity:
(S)-(+)-Camptothecin is a specific inhibitor of DNA topoisomerase I (Topo I), isolated from Camptotheca acuminata.
CAS:
7689-03-4
Formula:
C20H16N2O4
Molecular Weight:
348.358
Pathway:
Apoptosis; DNA Damage/DNA Repair; Microbiology/Virology
Purity:
0.9952
SMILES:
CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4ccccc4cc3Cn1c2=O
Target:
Apoptosis; Influenza Virus; Topoisomerase; Antibiotic; Antifungal

References

1. Wall ME, et al. J Am Chem Soc, 1966, 88 (16), 3888?3890. 2. Luzzio MJ, et al. J Med Chem, 1995, 38(3), 395-401. 3. Giovanella BC, et al. Cancer Res, 1991, 51(11), 3052-3055. 4. Hentze H, et al. Hepatology, 2004, 39(5), 1311-1320. 5. Cheng F, et al. Oncogene, 2011, 30(33), 3599-3611.