H3B-6545 Hydrochloride
Code | Size | Price |
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TAR-T11530-5mg | 5mg | £302.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T11530-50mg | 50mg | £1,267.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T11530-100mg | 100mg | £2,103.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
H3B-6545 Hydrochloride is a selective, oral estrogen receptor covalent antagonist (SERCA).
CAS:
2052132-51-9
Formula:
C30H30ClF4N5O2
Molecular Weight:
604.05
Purity:
0.98
SMILES:
Cl.CN(C)C(=O)C=CCNCCOc1ccc(cn1)C(=C(CC(F)(F)F)c1ccccc1)c1ccc2[nH]nc(F)c2c1
References
1. Peter G. Smith, et al. Abstract DDT01-04: Discovery and development of H3B-6545: A novel, oral, selective estrogen receptor covalent antagonist (SERCA) for the treatment of breast cancer.AACR Annual Meeting 2017; April 1-5.
2. Manav Korpal, et al. Development of a First-in-Class Oral Selective ER Covalent Antagonist (SERCA) for the Treatment of ER?