HIF-2 α-IN-3
Code | Size | Price |
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TAR-T11562-5mg | 5mg | £304.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T11562-50mg | 50mg | £1,163.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T11562-100mg | 100mg | £1,564.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
HIF-2α-IN-3 is an allosteric inhibitor of HIF-2α (IC50: 0.4 μM; KD: 1.1 μM) with anticancer activity.
CAS:
313964-19-1
Formula:
C12H6ClN5O5
Molecular Weight:
335.66
Pathway:
Chromatin/Epigenetic; Angiogenesis
Purity:
0.98
SMILES:
[O-][N+](=O)c1cc(Nc2ccc3nonc3c2[N+]([O-])=O)ccc1Cl
Target:
HIF
References
1. Rogers JL, et al. Development of inhibitors of the PAS-B domain of the HIF-2? transcription factor. J Med Chem. 2013 Feb 28;56(4):1739-47.