TargetMol

Jaspamycin

Product Code:
 
TAR-T11711
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11711-5mg5mg£304.00
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TAR-T11711-50mg50mg£1,163.00
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Quantity:
TAR-T11711-100mg100mg£1,564.00
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Further Information

Bioactivity:
Jaspamycin (7-CN-7-C-Ino) does not bind with purified human PKARIα. Anti-parasite activity. Jaspamycin (7-CN-7-C-Ino) is a potent activator of PKA, binding to the R site (PKAR), with an EC50 of 6.5 nM and Kd of 8 nM in Trypanosoma brucei.
CAS:
22242-96-2
Formula:
C12H12N4O5
Molecular Weight:
292.251
Pathway:
Angiogenesis; JAK/STAT signaling; Stem Cells; Chromatin/Epigenetic
Purity:
0.98
SMILES:
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cc(C#N)c2c1nc[nH]c2=O
Target:
JAK

References

1. Sabine Bachmaier, et al. Nucleoside analogue activators of cyclic AMP-independent protein kinase A of Trypanosoma. Nat Commun. 2019 Mar 29;10(1):1421.