Necrostatin 2 S enantiomer
Code | Size | Price |
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TAR-T12203-50mg | 50mg | £790.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
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Further Information
Bioactivity:
Necrostatin 2 S enantiomer is the S enantiomer of Necrostatin 2
CAS:
852391-20-9
Formula:
C13H12ClN3O2
Molecular Weight:
277.71
Purity:
0.98
SMILES:
CN1C(=O)N[C@@H](Cc2c[nH]c3c(Cl)cccc23)C1=O
References
1. Teng X, Keys H, Jeevanandam A, Structure-activity relationship study of [1,2,3]thiadiazole necroptosis inhibitors. Bioorg Med Chem Lett. 2007 Dec 15;17(24):6836-40.
2. Takahashi N, et al. Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models. Cell Death Dis. 2012 Nov 29;3:e437.
3. Jagtap PG, Degterev A, Choi S, Structure-activity relationship study of tricyclic necroptosis inhibitors. J Med Chem. 2007 Apr 19;50(8):1886-95.
4. Teng X, Degterev A, Jagtap P, Structure-activity relationship study of novel necroptosis inhibitors. Bioorg Med Chem Lett. 2005 Nov 15;15(22):5039-44.