I-BET762 carboxylic acid
Code | Size | Price |
---|
TAR-T13086-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T13086-50mg | 50mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
I-BET762 carboxylic acid is an inhibitor of BRD4(pIC50 of 5.1).
CAS:
1300019-38-8
Formula:
C20H17ClN4O3
Molecular Weight:
396.83
Pathway:
Chromatin/Epigenetic
Purity:
0.98
SMILES:
COc1ccc-2c(c1)C(=N[C@@H](CC(O)=O)c1nnc(C)n-21)c1ccc(Cl)cc1
Target:
Epigenetic Reader Domain
References
1. Mirguet O, et al. Discovery of epigenetic regulator I-BET762: lead optimization to afford a clinical candidate inhibitor of the BET bromodomains. J Med Chem. 2013 Oct 10;56(19):7501-15.