WEHI-539 hydrochloride
Code | Size | Price |
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TAR-T13337-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T13337-50mg | 50mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
WEHI-539 hydrochloride is a selective Bcl-XL inhibitor (IC50: 1.1 nM).
CAS:
2070018-33-4
Formula:
C31H30ClN5O3S2
Molecular Weight:
620.18
Pathway:
Apoptosis
Purity:
0.98
SMILES:
Cl.NCc1ccc(OCCCc2sc(nc2C(O)=O)-c2ccc3CCCC(=N/Nc4nc5ccccc5s4)c3c2)cc1
Target:
BCL
References
1. Lessene G, et al. Structure-guided design of a selective BCL-X(L) inhibitor. Nat Chem Biol. 2013 Jun;9(6):390-7.
2. Abed MN, et al. Antagonism of Bcl-XL is necessary for synergy between NSC 241240 and BH3 mimetics in ovarian cancer cells. J Ovarian Res. 2016 Apr 14;9:25.