AMP-PCP disodium
Code | Size | Price |
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TAR-T13547L-50mg | 50mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
AMP-PCP disodium is an ATP analog and can bind to the Hsp90 N-terminal domain (Kd: 3.8 μM). AMP-PCP binding favors the formation of the active homodimer of Hsp90.
CAS:
7414-56-4
Formula:
C11H16N5Na2O12P3
Molecular Weight:
549.173
Pathway:
Metabolism; Cytoskeletal Signaling
Purity:
0.98
SMILES:
Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP(=O)(CP(O)(=O)O[Na])O[Na])[C@@H](O)[C@H]1O
Target:
HSP
References
1. Zhang H, et al. A dynamic view of ATP-coupled functioning cycle of Hsp90 N-terminal domain. Sci Rep. 2015 Apr 13;5:9542.