AZD8329
| Code | Size | Price |
|---|
| TAR-T14383-50mg | 50mg | £870.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T14383-100mg | 100mg | £1,468.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
AZD8329 is a potent inhibitor of 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1)(IC50 of 9 nM for human 11β-HSD1), and displays excellent selectivity versus 11β-HSD2, 17β-HSD1 and 17β-HSD3.
CAS:
1048668-70-7
Formula:
C25H31N3O3
Molecular Weight:
421.541
Pathway:
Metabolism
Purity:
0.98
SMILES:
CC(C)(C)c1c(cnn1-c1ccc(cc1)C(O)=O)C(=O)NC1C2CC3CC(C2)CC1C3
Target:
Dehydrogenase
References
1. Scott JS, et al. Novel acidic 11?-hydroxysteroid dehydrogenase type 1 (11?-HSD1) inhibitor with reduced acyl glucuronide liability: the discovery of 4-[4-(2-adamantylcarbamoyl)-5-tert-butyl-pyrazol-1-yl]benzoic acid (AZD8329). J Med Chem. 2012 Nov 26;55(22):10136-47.