GSK2194069
Code | Size | Price |
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TAR-T15429-50mg | 50mg | £537.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T15429-1mL | 1 mL * 10 mM (in DMSO) | £551.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
GSK2194069 is a specific inhibitor of the β-ketoacyl reductase (KR) activity of hFAS (IC50: 7.7 ? 4.1 nM in an assay detecting released CoA).
CAS:
1332331-08-4
Formula:
C25H24N4O3
Molecular Weight:
428.492
Pathway:
Others|Metabolism
Purity:
0.98
SMILES:
O=C(C1CC1)N1CC[C@@H](Cc2n[nH]c(=O)n2-c2ccc(cc2)-c2ccc3occc3c2)C1
Target:
Others|Fatty Acid Synthase|NADPH
References
1. Hardwicke MA, et al. A human fatty acid synthase inhibitor binds ?-ketoacyl reductase in the keto-substrate site. Nat Chem Biol. 2014 Sep;10(9):774-9.