Propargyl-PEG3-acid
Code | Size | Price |
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TAR-T16605-50mg | 50mg | £104.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Propargyl-PEG3-acid is a non-cleavable (3-unit PEG) ADC linker. Propargyl-PEG3-acid is also a PEG-based PROTAC linker used to synthesize 6-OHDA-PEG3-yne. 6-OHDA-PEG3-yne contains 6-OHDA and Propargyl-PEG3-acid[1].
CAS:
1347760-82-0
Formula:
C10H16O5
Molecular Weight:
216.233
Pathway:
PROTAC
Purity:
0.98
SMILES:
OC(=O)CCOCCOCCOCC#C
Target:
PROTAC Linker
References
1. Farzam A, et al. A functionalized hydroxydopamine quinone links thiol modification to neuronal cell death. Redox Biol. 2020 Jan;28:101377.
2. Albone, Earl F, et al. ERIBULIN-BASED ANTIBODY-DRUG CONJUGATES AND METHODS OF USE. Patent. 20170252458.