Genistein
Code | Size | Price |
---|
TAR-T1737-50mg | 50mg | £101.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T1737-100mg | 100mg | £114.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T1737-1mL | 1 mL * 10 mM (in DMSO) | £116.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T1737-500mg | 500mg | £148.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Genistein is an isoflavonoid derived from soy products. It inhibits protein-tyrosine kinase and topoisomerase-II (DNA TOPOISOMERASES, TYPE II), with antineoplastic and antitumor activities.
CAS:
446-72-0
Formula:
C15H10O5
Molecular Weight:
270.24
Pathway:
Apoptosis; Metabolism; Tyrosine Kinase/Adaptors; Autophagy; JAK/STAT signaling; Angiogenesis
Purity:
0.9969
SMILES:
Oc1ccc(cc1)-c1coc2cc(O)cc(O)c2c1=O
Target:
Apoptosis; EGFR; Endogenous Metabolite; Autophagy
References
1. Akiyama T, et al. J Biol Chem, 1987, 262(12), 5592-5595.
2. Linassier C, et al. Biochem Pharmacol, 1990, 39(1), 187-193.
3. Dang ZC, et al. J Biol Chem, 2003, 278(2), 962-967.
4. Lamartiniere CA, et al. J Nutr, 2002, 132(3), 552S-558S.
5. Wang Y, et al. Radiat Res, 2006, 166(1 Pt 1), 73-80.
6. Jalili C, et al. Effect of Genistein on reproductive parameter and serum nitric oxide levels in morphine-treated mice. Int J Reprod Biomed (Yazd). 2016 Feb;14(2):95-102.
7. Ding S, et al. Environmentally Relevant Dose of Bisphenol A Does Not Affect Lipid Metabolism and Has No Synergetic or Antagonistic Effects on Genistein's Beneficial Roles on Lipid Metabolism. PLoS One. 2016 May 12;11(5):e0155352.
8. Zhou H, Ning Y, Zeng G, et al. Curcumin promotes cell cycle arrest and apoptosis of acute myeloid leukemia cells by inactivating AKT[J]. Oncology Reports. 2021, 45(4): 1-1.