Dynorphin A (1-8)
| Code | Size | Price |
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| TAR-T20403-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| TAR-T20403-50mg | 50mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Dynorphin (1-8) is an opioid octapeptide from the porcine hypothalamus. It comprises the N-terminal eight residues of dynorphin.
CAS:
75790-53-3
Formula:
C46H72N14O10
Molecular Weight:
981.17
Purity:
0.98
SMILES:
CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O
References
1. Al-Hossaini AM, Suntornsuk L, Lunte SM. Separation of dynorphin peptides by capillary electrochromatography using a polydiallyldimethylammonium chloride gold nanoparticle-modified capillary. Electrophoresis. 2016 Sep;37(17-18):2297-304. doi: 10.1002/elps.201600006. Epub 2016 Jun 16. PubMed PMID: 27130293; PubMed Central PMCID: PMC5283704.
2. Brust A, Croker DE, Colless B, Ragnarsson L, Andersson ?, Jain K, Garcia-Caraballo S, Castro J, Brierley SM, Alewood PF, Lewis RJ. Conopeptide-Derived ?-Opioid Agonists (Conorphins): Potent, Selective, and Metabolic Stable Dynorphin A Mimetics with Antinociceptive Properties. J Med Chem. 2016 Mar 24;59(6):2381-95. doi: 10.1021/acs.jmedchem.5b00911. Epub 2016 Feb 22. PubMed PMID: 26859603.
3. Moln?r CS, S?rv?ri M, Vastagh C, Maurnyi C, Fekete C, Liposits Z, Hrabovszky E. Altered Gene Expression Profiles of the Hypothalamic Arcuate Nucleus of Male Mice Suggest Profound Developmental Changes in Peptidergic Signaling. Neuroendocrinology. 2016;103(3-4):369-82. doi: 10.1159/000439430. Epub 2015 Aug 25. PubMed PMID: 26338351.
4. Caldwell AS, Eid S, Kay CR, Jimenez M, McMahon AC, Desai R, Allan CM, Smith JT, Handelsman DJ, Walters KA. Haplosufficient genomic androgen receptor signaling is adequate to protect female mice from induction of polycystic ovary syndrome features by prenatal hyperandrogenization. Endocrinology. 2015 Apr;156(4):1441-52. doi: 10.1210/en.2014-1887. Epub 2015 Feb 2. PubMed PMID: 25643156.