(R)-Propranolol hydrochloride

TargetMol
Product Code: TAR-T20898
Supplier: TargetMol
CodeSizePrice
TAR-T20898-50mg50mgEnquire
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TAR-T20898-25mg25mg£99.00
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Quantity:
TAR-T20898-1mL1 mL * 10 mM (in DMSO)£111.00
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Dexpropranolol hydrochloride is the less active enantiomer of the anti-adrenoceptor (β-adrenoceptor) antagonist propranolol. Propranolol is a nonselective β-adrenergic receptor (βAR) antagonist with a high affinity for β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively.
CAS:
13071-11-9
Formula:
C16H22ClNO2
Molecular Weight:
295.81
Pathway:
GPCR/G Protein; Neuroscience
Purity:
0.9901
SMILES:
Cl.CC(C)NC[C@@H](O)COc1cccc2ccccc12
Target:
Adrenergic Receptor

References

1. Cocker PJ, Lin MY, Tremblay M, Kaur S, Winstanley CA. The ?-adrenoceptor blocker propranolol ameliorates compulsive-like gambling behaviour in a rodent slot machine task:implications for iatrogenic gambling disorder. Eur J Neurosci. 2018 Jul 17. 2. B?hrer C, Erdeve ?, Bassler D, Bar-Oz B. Oral propranolol for prevention of threshold retinopathy of prematurity (ROPROP):protocol of a randomised controlled trial. BMJ Open. 2018 Jul 6;8(7):e021749. 3. Zhu X, Guo X, Liu D, Gong Y, Sun J, Dong C. Promotion of Propranolol Delivery to Hemangiomas by Using Anti-VEGFR Antibody-Conjugated Poly(lactic-co-glycolic acid) Nanoparticles. J Biomed Nanotechnol. 2017 Dec 1;13(12):1694-1705. 4. AM, Cullum VA. The biological properties of the optical isomers of propranolol and their effects on cardiac arrhythmias. Br J Pharmacol. 1968 Sep;34(1):43-55.