Rifamycin
| Code | Size | Price |
|---|
| TAR-T21225-50mg | 50mg | £264.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T21225-100mg | 100mg | £402.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T21225-500mg | 500mg | £772.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Rifamycin, a natural antibiotic, inhibits prokaryotic DNA-dependent RNA synthesis and protein synthesis, leading to the block of RNA-polymerase transcription initiation.
CAS:
6998-60-3
Formula:
C37H47NO12
Molecular Weight:
697.778
Purity:
0.98
SMILES:
CO[C@H]1C=C/O[C@@]2(C)Oc3c(C2=O)c2c(O)cc(NC(=O)C(C)=C/C=C[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)c(O)c2c(O)c3C
References
1. Rosette C, Agan FJ, Rosette N, Moro L, Mazzetti A, Hassan C, Gerloni M. Rifamycin SV exhibits strong anti-inflammatory in vitro activity through pregnane X receptor stimulation and NF?B inhibition. Drug Metab Pharmacokinet. 2019 Jun;34(3):172-180. doi: 10.1016/j.dmpk.2019.01.002. Epub 2019 Jan 17. PubMed PMID: 31101589.
2. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from http://www.ncbi.nlm.nih.gov/books/NBK540689/ PubMed PMID: 31038854.
3. Steffen R, DuPont HL. Rifamycin SV-MMX? as the recommended self-treatment for moderate to severe travellers' diarrhoea: reply. J Travel Med. 2019 May 10;26(3). pii: taz014. doi: 10.1093/jtm/taz014. PubMed PMID: 30848824; PubMed Central PMCID: PMC6509471.
4. Ericsson CD, Connor BA, Riddle MS. When should travel medicine practitioners prescribe Rifamycin SV-MXX for self-treatment of travellers' diarrhoea? J Travel Med. 2019 May 10;26(3). pii: taz013. doi: 10.1093/jtm/taz013. PubMed PMID: 30848819.