Cyclizine

TargetMol
Product Code: TAR-T21379
Supplier: TargetMol
CodeSizePrice
TAR-T21379-5mg5mg£850.00
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Quantity:
TAR-T21379-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T21379-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Cyclizine, an antihistamine drug, is used to treat dizziness, nausea and vomiting associated with motion sickness, vertigo and post-operatively following administration of general anaesthesia and opioids. Cyclizine is a histamine H1 antagonist.
CAS:
82-92-8
Formula:
C18H22N2
Molecular Weight:
266.388
Purity:
0.98
SMILES:
CN1CCN(CC1)C(c1ccccc1)c1ccccc1

References

1. Borukhova S, No?l T, Hessel V. Continuous-Flow Multistep Synthesis of Cinnarizine, Cyclizine, and a Buclizine Derivative from Bulk Alcohols. ChemSusChem. 2015 Dec 9. doi: 10.1002/cssc.201501367. [Epub ahead of print] PubMed PMID: 26663906. 2. Arnestad M, Eldor KB, Stray-Pedersen A, Bachs L, Karinen R. Suicide due to cyclizine overdose. J Anal Toxicol. 2014 Mar;38(2):110-2. doi: 10.1093/jat/bkt100. Epub 2013 Dec 8. PubMed PMID: 24324230. 3. Ahmadi A, Khalili M, Chavrogh S, Nahri-Niknafs B. Synthesis and Anti-inflammatory Performance of Newly Cyclizine Derivatives on Adult Male Wistar Rats. Iran J Pharm Res. 2012 Fall;11(4):1027-37. PubMed PMID: 24250533; PubMed Central PMCID: PMC3813157. 4. Wojcikiewicz TG, Peck MJ. Transient paralysis after cyclizine administration. Anaesthesia. 2013 Dec;68(12):1284-5. doi: 10.1111/anae.12515. PubMed PMID: 24219270.