Pirfenidone
Code | Size | Price |
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TAR-T2386-50mg | 50mg | £104.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T2386-100mg | 100mg | £119.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T2386-200mg | 200mg | £129.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T2386-500mg | 500mg | £148.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T2386-1g | 1g | £189.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Pirfenidone is an inhibitor for TGF-β production and TGF-β stimulated collagen production. Pirfenidone inhibits fibroblast, epidermal, platelet-derived, and transforming beta-1 growth factors, thereby slowing tumor cell proliferation. This agent also inhibits DNA synthesis and the production of mRNA for collagen types I and III, resulting in a reduction in radiation-induced fibrosis.
CAS:
53179-13-8
Formula:
C12H11NO
Molecular Weight:
185.226
Pathway:
Immunology/Inflammation; Stem Cells; Microbiology/Virology
Purity:
0.9993
SMILES:
Cc1ccc(=O)n(c1)-c1ccccc1
Target:
CCR; TGF-beta/Smad
References
1. Nakazato H, et al. Eur J Pharmacol, 2002, 446(1-3), 177-185.
2. Burghardt I, et al. Biochem Biophys Res Commun, 2007, 354(2), 542-547.
3. Shihab FS, et al. Am J Transplant, 2002, 2(2), 111-119.
4. Kakugawa T, et al. Eur Respir J, 2004, 24(1), 57-65.
5. Di Sario A, et al. Dig Liver Dis, 2004, 36(11), 744-751.