Cellocidin
| Code | Size | Price |
|---|
| TAR-T23872-50mg | 50mg | £932.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Cellocidin is a potent gammaherpesvirus-associated B-lymphomas growth inhibitor. It acts through the activation of both the NF-κB and c-Myc-mediated signaling pathways.
CAS:
543-21-5
Formula:
C4H4N2O2
Molecular Weight:
112.088
Purity:
0.98
SMILES:
NC(=O)C#CC(N)=O
References
1. Otoguro K, Ishiyama A, Namatame M, Nishihara A, Furusawa T, Masuma R, Shiomi K, Takahashi Y, Yamada H, Omura S. Selective and potent in vitro antitrypanosomal activities of ten microbial metabolites. J Antibiot (Tokyo). 2008 Jun;61(6):372-8. doi: 10.1038/ja.2008.52. PubMed PMID: 18667785.
2. Yoneyama K, Sekido S, Misato T. Antagonistic mechanism of sulfhydryl compounds on cellocidin activity. J Antibiot (Tokyo). 1978 Oct;31(10):1065-6. PubMed PMID: 711614.
3. Jones ER, Keeping JW, Pellatt MG, Thaller V. Natural acetylenes. 38. Biosyntheses of acetylenedicarboxamide (cellocidin) in Streptomyces SF-536 cultures. J Chem Soc Perkin 1. 1973;2:148-50. PubMed PMID: 4736298.
4. SUZUKI S, OKUMA K. The structure of cellocidin. J Antibiot (Tokyo). 1958 May;11(3):84-6. PubMed PMID: 13563327.