CRT-0105950
Code | Size | Price |
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TAR-T23917-50mg | 50mg | £670.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T23917-100mg | 100mg | £1,026.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
CRT-0105950 is an effective LIMK inhibitor that acts by suppressing cofilin phosphorylation and increasing αTubulin acetylation in cells.
CAS:
1661845-86-8
Formula:
C21H16ClN3OS
Molecular Weight:
393.89
Purity:
0.98
SMILES:
Cc1ccc(c(Cl)c1)-c1cnccc1-c1cnc(Nc2ccc(O)cc2)s1
References
1. Mardilovich K, Baugh M, Crighton D, Kowalczyk D, Gabrielsen M, Munro J, Croft DR, Lourenco F, James D, Kalna G, McGarry L, Rath O, Shanks E, Garnett MJ, McDermott U, Brookfield J, Charles M, Hammonds T, Olson MF. LIM kinase inhibitors disrupt mitotic microtubule organization and impair tumor cell proliferation. Oncotarget. 2015 Nov 17;6(36):38469-86. doi: 10.18632/oncotarget.6288. PubMed PMID: 26540348; PubMed Central PMCID: PMC4770715.