A-85380 HCl
| Code | Size | Price |
|---|
| TAR-T26489-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T26489-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T26489-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
A-85380 is an agonist of nicotinic acetylcholine receptor.
CAS:
174740-86-4
Formula:
C9H14Cl2N2O
Molecular Weight:
237.12
Purity:
0.98
SMILES:
Cl.Cl.C(Oc1cccnc1)[C@@H]1CCN1
References
1. Lagarde J, Sarazin M, Chauvir? V, Stankoff B, Kas A, Lacomblez L, Peyronneau MA, Bottlaender M. Cholinergic Changes in Aging and Alzheimer Disease: An [18F]-F-A-85380 Exploratory PET Study. Alzheimer Dis Assoc Disord. 2016 Sep 27. [Epub ahead of print] PubMed PMID: 27680780.
2. Le Foll B, Chefer SI, Kimes AS, Stein EA, Goldberg SR, Mukhin AG. Impact of short access nicotine self-administration on expression of ?4?2* nicotinic acetylcholine receptors in non-human primates. Psychopharmacology (Berl). 2016 May;233(10):1829-35. doi: 10.1007/s00213-016-4250-9. PubMed PMID: 26911381; PubMed Central PMCID: PMC4846528.
3. Miyauchi M, Neugebauer NM, Oyamada Y, Meltzer HY. Nicotinic receptors and lurasidone-mediated reversal of phencyclidine-induced deficit in novel object recognition. Behav Brain Res. 2016 Mar 15;301:204-12. doi: 10.1016/j.bbr.2015.10.044. PubMed PMID: 26519556.
4. Ogunjirin AE, Fortunak JM, Brown LL, Xiao Y, D?vila-Garc?a MI. Competition, Selectivity and Efficacy of Analogs of A-84543 for Nicotinic Acetylcholine Receptors with Repositioning of Pyridine Nitrogen. Neurochem Res. 2015 Oct;40(10):2131-42. doi: 10.1007/s11064-015-1705-z. PubMed PMID: 26508288; PubMed Central PMCID: PMC4741274.