Honokiol DCA
Code | Size | Price |
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TAR-T27551-50mg | 50mg | £704.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T27551-100mg | 100mg | £962.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Honokiol DCA is an inhibitor of DRP1 phosphorylation. Honokiol DCA stimulates a phenotype suggestive of respiration through mitochondrial normalization and demonstrating activity in Vemurafenib-resistant melanoma in vivo.
CAS:
1620160-42-0
Formula:
C22H18Cl4O4
Molecular Weight:
488.18
Purity:
0.98
SMILES:
ClC(Cl)C(=O)Oc1c(CC=C)cc(-c2ccccc2)c(OC(=O)C(Cl)Cl)c1CC=C
References
1. Bonner MY, Karlsson I, Rodolfo M, Arnold RS, Vergani E, Arbiser JL. Honokiol bis-dichloroacetate (Honokiol DCA) demonstrates activity in vemurafenib-resistant melanoma in vivo. Oncotarget. 2016 Mar 15;7(11):12857-68. doi: 10.18632/oncotarget.7289. PubMed PMID: 26871475; PubMed Central PMCID: PMC4914326.