OB-1
| Code | Size | Price |
|---|
| TAR-T28223-50mg | 50mg | £946.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
OB-1 is an inhibitor of stomatin-like protein-3 (STOML3) oligomerization. OB-1 reversibly reduces the sensitivity of mechanically gated currents in sensory neurons and silence mechanoreceptors in vivo.
CAS:
300803-69-4
Formula:
C21H17N3O6
Molecular Weight:
407.382
Purity:
0.98
SMILES:
CCOC(=O)c1c(oc2ccc(Oc3c(ncn3C)[N+]([O-])=O)cc12)-c1ccccc1
References
1. Vileigas DF, de Deus AF, da Silva DC, de Tomasi LC, de Campos DH, Adorni CS, de Oliveira SM, Sant'Ana PG, Okoshi K, Padovani CR, Cicogna AC. Saturated high-fat diet-induced obesity increases adenylate cyclase of myocardial ?-adrenergic system and does not compromise cardiac function. Physiol Rep. 2016 Sep;4(17). pii: e12914. doi: 10.14814/phy2.12914. PubMed PMID: 27582064; PubMed Central PMCID: PMC5027348.
2. Raju J, Roberts J, Chen Q, Aziz SA, Caldwell D, Bird RP, Scoggan KA, Brooks SP. Fermentable Carbohydrates Differentially Affect Colon Tumor Formation in Azoxymethane-Induced Male Fischer 344 Rats. J Nutr. 2016 Mar 9. pii: jn214833. [Epub ahead of print] PubMed PMID: 26962187.
3. Martins BC, Plummer CE, Gelatt KN, Brooks DE, Czerwinski SE, Monk C, Greenberg SM, Mangan BG, Londo?o L, Bolfer L, Bandt C, Schaer M. Ophthalmic abnormalities secondary to periocular or ocular snakebite (pit vipers) in dogs--11 cases (2012-2014). Vet Ophthalmol. 2016 Mar;19(2):149-60. doi: 10.1111/vop.12276. Epub 2015 Apr 24. PubMed PMID: 25912317.
4. Liechty JM, Lee MJ. Body size estimation and other psychosocial risk factors for obesity onset among US adolescents: findings from a longitudinal population level study. Int J Obes (Lond). 2015 Apr;39(4):601-7. doi: 10.1038/ijo.2014.191. Epub 2014 Nov 5. PubMed PMID: 25370575.