NLRP3-IN-2
Code | Size | Price |
---|
TAR-T3230-50mg | 50mg | £103.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T3230-1mL | 1 mL * 10 mM (in DMSO) | £107.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T3230-100mg | 100mg | £113.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T3230-200mg | 200mg | £132.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
It is a NLRP3 Inflammasome Inhibitor I.
CAS:
16673-34-0
Formula:
C16H17ClN2O4S
Molecular Weight:
368.83
Pathway:
Immunology/Inflammation; NF-κb
Purity:
0.9898
SMILES:
COc1ccc(Cl)cc1C(=O)NCCc1ccc(cc1)S(N)(=O)=O
Target:
NOD-like Receptor (NLR); NOD
References
1. Baldwin, A., Brough, D., & Freeman, S. (2015). Inhibiting the Inflammasome: A Chemical Perspective.?Journal Of Medicinal Chemistry,?59(5), 1691-1710. doi: 10.1021/acs.jmedchem.5b01091
2. Marchetti, C., Chojnacki, J., Toldo, S., Mezzaroma, E., Tranchida, N., & Rose, S. et al. (2014). A Novel Pharmacologic Inhibitor of the NLRP3 Inflammasome Limits Myocardial Injury After Ischemia?Reperfusion in the Mouse.?Journal Of Cardiovascular Pharmacology,?63(4), 316-322. doi: 10.1097/fjc.202002020020200200020053