Sodium dichloroacetate
Code | Size | Price |
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TAR-T3604-50mg | 50mg | £95.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T3604-100mg | 100mg | £107.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T3604-1mL | 1 mL * 10 mM (in DMSO) | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T3604-200mg | 200mg | £117.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Dichloroacetate, a specific inhibitor of pyruvate dehydrogenase kinase (PDK) with IC50 values of 183 and 80 μM for PDK2 and PDK4 respectively, has been shown to derepress a mitochondrial potassium-ion channel axis, trigger apoptosis in cancer cells, and inhibit tumor growth.
CAS:
2156-56-1
Formula:
C2HCl2NaO2
Molecular Weight:
150.92
Pathway:
PI3K/Akt/mTOR signaling; Metabolism; NF-κb; Apoptosis; Immunology/Inflammation
Purity:
0.9987
SMILES:
[Na+].[O-]C(=O)C(Cl)Cl
Target:
Apoptosis; Dehydrogenase; Reactive Oxygen Species; PDK
References
Bowker-Kinley MM, et al. Biochem J. 1998 Jan 1;329 ( Pt 1):191-6.
Bonnet S, et al. Y Cell. 2007 Jan;11(1):37-51.