PD 144418 oxalate

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TargetMol
Product Code: TAR-T39211
Supplier: TargetMol
CodeSizePrice
TAR-T39211-1mg1mg£148.00
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TAR-T39211-2mg2mg£185.00
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TAR-T39211-5mg5mg£270.00
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TAR-T39211-10mg10mg£367.00
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TAR-T39211-25mg25mg£550.00
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TAR-T39211-50mg50mg£765.00
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TAR-T39211-100mg100mg£1,002.00
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TAR-T39211-500mg500mg£1,942.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
PD 144418 oxalate is a highly affinity, potent and selective sigma 1 (σ1) receptor ligand ( K i values of 0.08 nM and 1377 nM for σ1 and σ2 respectively). PD 144418 oxalate devoids of any significant affinity for other receptors, ion channels and enzymes. PD 144418 oxalate shows potential antipsychotic activity.
CAS:
1794760-28-3
Formula:
0
Molecular Weight:
0
Pathway:
GPCR/G Protein
Purity:
0.98
SMILES:
0
Target:
Sigma receptor

References

Lever JR, et al. Relationship between cerebral sigma-1 receptor occupancy and attenuation of cocaine's motor stimulatory effects in mice by PD144418. J Pharmacol Exp Ther. 2014 Oct;351(1):153-63. Akunne HC, et al. The pharmacology of the novel and selective sigma ligand, PD 144418. Neuropharmacology. 1997 Jan;36(1):51-62.