TRV120055
| Code | Size | Price |
|---|
| TAR-T39995-50mg | 50mg | £788.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
TRV120055 is a G q -biased agonists, exhibits 10-fold larger molecular efficacies at the AT 1 R-Gq fusion protein compared with the AT 1 R-βarr2 fusion protein.
CAS:
2410957-04-7
Formula:
0
Molecular Weight:
0
Purity:
0.98
SMILES:
0
References
Rajagopal S, et, al. Quantifying ligand bias at seven-transmembrane receptors. Mol Pharmacol. 2011 Sep;80(3):367-77.
Strachan RT, et, al. Divergent transducer-specific molecular efficacies generate biased agonism at a G protein-coupled receptor (GPCR). J Biol Chem. 2014 May 16; 289(20): 14211-24.