TargetMol

Rotundine

Product Code:
 
TAR-T6648
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6648-50mg50mg£114.00
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Quantity:
TAR-T6648-1mL1 mL * 10 mM (in DMSO)£118.00
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TAR-T6648-100mg100mg£132.00
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Quantity:
TAR-T6648-500mg500mg£227.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Rotundine (L-tetrahydropalmatine, L-THP) is a selective dopamine D1 receptor antagonist with IC50 of 166 nM.
CAS:
483-14-7
Formula:
C21H25NO4
Molecular Weight:
355.434
Pathway:
GPCR/G Protein; Neuroscience
Purity:
0.998
SMILES:
COc1cc2CCN3Cc4c(C[C@H]3c2cc1OC)ccc(OC)c4OC
Target:
Dopamine Receptor; 5-HT Receptor

References

Wu D, Wang P, Zhao C, et al.Levo-tetrahydropalmatine Ameliorates Neuropathic Pain by Inhibiting the Activation of the Clec7a-MAPK/NF-?B-NLRP3 Inflammasome Axis.Phytomedicine.2023: 155075. Liu YL, et al. Acta Pharmacol Sin, 2005, 26(5), 533-538. Wang JB, et al. Future Med Chem, 2012, 4(2), 177-186.