DL-Buthionine-(S,R)-sulfoximine
| Code | Size | Price |
|---|
| TAR-T7708-50mg | 50mg | £107.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
D,L-Buthionine-(S,R)-sulfoximine is an inhibitor of γ-glutamylcysteine synthetase for the treatment of solid tumors.
CAS:
5072-26-4
Formula:
C8H18N2O3S
Molecular Weight:
222.3
Pathway:
; Cell Cycle/Checkpoint; Apoptosis
Purity:
0.9832
SMILES:
CCCCS(=N)(=O)CCC(N)C(O)=O
Target:
Ferroptosis
References
Vanhoefer U , Cao S , Minderman H , et al. d,l-buthionine-(S,R)-sulfoximine potentiates in vivo the therapeutic efficacy of doxorubicin against multidrug resistance protein-expressing tumors.[J]. Clinical Cancer Research An Official Journal of the American Association for Cancer Research, 1996, 2(12):1961.
Arrick, B. A . Inhibition of glutathione synthesis as a chemotherapeutic strategy for trypanosomiasis[J]. Journal of Experimental Medicine, 1981, 153(3):720-725.