Nisoldipine
Code | Size | Price |
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TAR-T0163-100mg | 100mg | £103.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T0163-1mL | 1 mL * 10 mM (in DMSO) | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T0163-500mg | 500mg | £117.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T0163-1g | 1g | £146.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Nisoldipine is a dihydropyridine calcium channel antagonist that acts as a potent arterial vasodilator and antihypertensive agent.
CAS:
63675-72-9
Formula:
C20H24N2O6
Molecular Weight:
388.42
Pathway:
Membrane transporter/Ion channel; Metabolism; Immunology/Inflammation; NF-κb
Purity:
0.9957
SMILES:
COC(=O)C1=C(C)NC(C)=C(C1c1ccccc1[N+]([O-])=O)C(=O)OCC(C)C
Target:
Calcium Channel; Reactive Oxygen Species
References
1. Morel N, et al. Br J Pharmacol, 1998, 125(5), 12005-12012.
2. Missan S, et al. Br J Pharmacol, 2003, 140 (5), 863-870.
3. Sugawara H, et al. Hypertens Res, 1996, 19 (4), 223-228.
4. Iimuro Y, et al. Hepatology, 1996, 24(2), 391-397.
5. Splawski I, et al. Cell, 2004, 119 (1), 19-31.
6. Li W H, Huang K, Cai Y, et al. Permeant Fluorescent Probes Visualize the Activation of SARM1 and Uncover an Anti-neurodegenerative Drug Candidate[J]. Elife. 2021, 10: e67381.