TargetMol

Protocatechuic acid

Product Code:
 
TAR-T0562
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T0562-200mg200mg£109.00
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Quantity:
TAR-T0562-1mL1 mL * 10 mM (in DMSO)£114.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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Further Information

Bioactivity:
Protocatechuic acid (3, 4-dihydroxybenzoic acid) is a natural phenolic compound found in many edible and medicinal plants. Recent studies indicate that it could be used as a protective agent against cardiovascular diseases and neoplasms. The mechanism of its action is mostly associated with antioxidant activity, including inhibition of generation as well as scavenging of free radicals and up-regulating enzymes which participate in their neutralization.
CAS:
99-50-3
Formula:
C7H6O4
Molecular Weight:
154.121
Purity:
0.9985
SMILES:
OC(=O)c1ccc(O)c(O)c1

References

1. Thakare VN, et al. Attenuation of acute restraint stress-induced depressive like behavior and hippocampal alterations with protocatechuic acid treatment in mice. Metab Brain Dis. 2016 Oct 26. 2. Adefegha SA, et al. Alterations of Na+/K+-ATPase, cholinergic and antioxidant enzymes activity by protocatechuic acid in cadmium-induced neurotoxicity and oxidative stress in Wistar rats. Biomed Pharmacother. 2016 Oct;83:559-568. 3. Hornedo-Ortega R , ?lvarez-Fern?ndez, Mar?a Antonia, Cerezo, Ana Bel?n, et al. Protocatechuic acid: inhibition of fibril formation, destabilization of pre-formed fibrils of Amyloid-? and ?-Synuclein, and neuroprotection[J]. Journal of Agricultural and Food Chemistry, 2016:acs.jafc.6b03217. 4. Jang S A, Hwang Y H, Kim T, et al. Anti-Osteoporotic and Anti-Adipogenic Effects of the Water Extract of Drynaria roosii Nakaike in Ovariectomized Mice Fed a High-Fat Diet[J]. Molecules. 2019, 24(17): 3051. 5. Dong Q, Li Y, Liu G, et al. High oxygen treatments enhance the contents of phenolic compound and ganoderic acid, antioxidant and DNA damage protective activities of Ganoderma lingzhi fruiting body[J]. Frontiers in Microbiology. 2019, 10: 2363. 6. Chen Q, Sun D, Fang T, et al. In vitro allelopathic effects of compounds from Cerbera manghas L. on three Dinophyta species responsible for harmful common red tides. Science of The Total Environment. 2020: 142253.