Ganciclovir
| Code | Size | Price |
|---|
| TAR-T0688-1mL | 1 mL * 10 mM (in DMSO) | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T0688-100mg | 100mg | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T0688-1g | 1g | £131.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Ganciclovir is an ACYCLOVIR analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.
CAS:
82410-32-0
Formula:
C9H13N5O4
Molecular Weight:
255.234
Pathway:
Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology;
Purity:
0.9955
SMILES:
Nc1nc2n(COC(CO)CO)cnc2c(=O)[nH]1
Target:
Nucleoside Antimetabolite/Analog; Antibiotic; Antifection; HSV
References
1. Matthews T, et al. Rev Infect Dis, 1988, 10, S490-494.
2. Hamel W, et al. Cancer Res, 1996, 56(12), 2697-2702.
3. St Clair MH, et al. Antimicrob Agents Chemother, 1987, 31(6), 844-849.
4. Wei SJ, et al. Exp Cell Res, 1998, 241(1), 66-75.
5. Rubsam LZ, et al. Cancer Res, 1998, 58(17), 3873-3882.
6. BoujemLa I, et al. Pharmacokinetics and tissue diffusion of ganciclovir in mice and rats. Antiviral Res. 2016 Aug;132:111-5.
7. Zhao M, Wang B, Zhang C, et al. The DJ1-Nrf2-STING axis mediates the neuroprotective effects of Withaferin A in Parkinson?s disease[J]. Cell Death & Differentiation. 2021: 1-19.
8. Wilbertz J H, Voigt F, Horvathova I, et al. Single-molecule imaging of mRNA localization and regulation during the integrated stress response[J]. Molecular cell. 2019 Mar 7;73(5):946-958.e7.
9. Horvathova I, Voigt F, Kotrys A V, et al. The dynamics of mRNA turnover revealed by single-molecule imaging in single cells[J]. Molecular cell. 2017 Nov 2;68(3):615-625.e9.